Ingestion of patulin, a mycotoxin primarily found in moldy fruits like apples and their products, can cause acute gastrointestinal disturbances such as nausea, vomiting, and intestinal issues in humans, and is linked to liver, spleen, and kidney damage in animals.
- Why here
- Patulin is a common food contaminant, particularly in apple-based products, and is heat-stable and water-soluble, meaning it can persist through food processing and be ingested directly through contaminated food and beverages.
- What would have to be true
- The World Health Organization (WHO) recommends a maximum concentration of 50 µg/L in apple juice, and the Joint FAO/WHO Expert Committee on Food Additives (JECFA) has set a provisional maximum tolerable daily intake (PMTDI) of 0.4 µg/kg body weight per day. The European Union enforces a maximum limit of 50 µg/kg in fruit juices and drinks, 25 µg/kg in solid apple products, and 10 µg/kg for products intended for infants and young children. The US FDA has a guidance level of 50 µg/L for apple juice and apple juice concentrates.
- The other side
- The International Agency for Research on Cancer (IARC) classifies patulin as a Group 3 carcinogen, meaning it is not classifiable as to its carcinogenicity to humans due to inadequate evidence, although animal studies have raised concerns.
- Toxicological effects of patulin mycotoxin on the mammalian system: an overview - PMC — nih.gov (2017) · regulator or public body
- Mycotoxins - FDA — fda.gov (2026) · regulator or public body
- Mitigation of Patulin in Fresh and Processed Foods and Beverages - PMC — nih.gov (2017) · regulator or public body
- Health risk assessment of Patulin intake through apples and apple-based foods sold in Qatar - PMC — nih.gov (2019) · regulator or public body
- 3 web articles (digicomply.com, wikipedia.org, affinisep.com), linked in the app.
- 2 community or commercial pages, not counted here.