Is red 27 lake (ci 45410) safe in food and drink?

Under the app's default Cautious lens, red 27 lake (ci 45410) in food and drink rates Swap: the app would put this near the top of your swap plan. 2 sourced concerns count (restricted, consensus tier; environmental, emerging tier). This is research with sources, not medical advice.

What do the Clean, Low, Watch and Swap levels mean?

They are cut from a continuous concern level the app computes from the sourced claims that the chosen evidence lens shows: each claim counts its concern class, tier weight, confidence and dose relevance, combined worst-first with a decay so one serious finding outweighs many small ones, then scaled by how much of the substance reaches you in this use. Clean is below 0.35, Low below 1.1, Watch below 2.0 and Swap above that, on a 0 to 3 scale.

Is Red 27 Lake (ci 45410) safe on skin (left on)?

Cosmetics2 uses researched6 sourced claims

Where it turns up: red pigment, lip, cheek color. Detox My Life researched red 27 lake (ci 45410) under 2 different uses, because the same substance means something different in each. Every claim below carries its evidence tier, how sure the research is that it applies here, and the sources it cites. The level is computed by the app's own deterministic engine, so the page says exactly what the app would.

Level by use and lens

Use	Mainstream	Cautious (default)	Based	Concerns · favour · fringe
On skin, left on	Swap	Swap	Swap	4 · 0
Eaten or drunk	Watch	Swap	Swap	2 · 0

Mainstream shows consensus claims only; Cautious adds emerging research; Based adds fringe claims, labelled as such. The last column counts, under Cautious, the sourced concerns, the findings in its favour and the fringe claims Based would add.

Safer swaps: the app's swap catalog has no entry tied to this ingredient yet. When you scan a product that contains it, the app suggests cleaner alternative types for that product; the swap categories list what the catalog covers today.

On skin, left on Swap

Under the default Cautious lens red 27 lake (ci 45410) on skin (left on) rates Swap: the app would put this near the top of your swap plan. Mainstream (consensus only) rates it Swap; Based (adds the fringe) rates it Swap. Researched 2026-09-03.

Sourced concerns (4)

ConsensusRestrictedconfidence 100%

Red 27 Lake (CI 45410) is not permitted for use in products intended for the eye area in the United States and is restricted from eye use in the EU and Japan.

Why here: This restriction directly applies to dermal leave-on cosmetic products, limiting their application areas.
What would have to be true: Dermal exposure in the eye area.

Sources the engine cites:

Red 27 Lake - Cosmetics Info — cosmeticsinfo.org (2026) · review
1 community or commercial page, not counted here.

EmergingSuspected carcinogenconfidence 60%

Synthetic petroleum-based dyes, including Red 27 Lake (CI 45410), have been generally associated with residues of heavy metals like lead and potential carcinogenicity, though regulatory bodies certify batches to meet strict specifications.

Why here: Dermal leave-on products can lead to prolonged exposure to ingredients and any associated impurities.
What would have to be true: Dermal contact with cosmetic products containing CI 45410 and potential impurities.
The other side: The FDA reviews the safety of Red 27 and Red 27 Lake and requires certification for all manufactured batches to ensure strict chemical and identity specifications are met, which includes controlling impurities.

Sources the engine cites:

Red 27 Lake - Cosmetics Info — cosmeticsinfo.org (2026) · review

EmergingEndocrineconfidence 60%

Red 27 Lake (CI 45410) has a low concern for endocrine disruption according to some databases.

Why here: As a leave-on product, there is prolonged skin contact, which is the route for potential endocrine disruptor exposure.
What would have to be true: Dermal contact with cosmetic products containing CI 45410.
The other side: Rigorous product safety assessments by scientific experts are legally obliged to cover all potential risks, including potential endocrine disruption, and many substances, including natural ones, mimic hormones but few cause disruption.

Sources the engine cites:

CI 45410 – Ingredient - COSMILE Europe — cosmileeurope.eu (2026) · review

EmergingIrritant · allergenconfidence 70%

CI 45410 (Red 27 Lake) is capable of causing skin and eye irritation, though some sources indicate it is irritant-free in certain contexts.

Why here: Direct contact with the skin in leave-on products could lead to irritation for sensitive individuals.
What would have to be true: Dermal contact with cosmetic products containing CI 45410.
The other side: SkinSAFE lists Red 27 Lake as 'Irritant Free'.

Sources the engine cites (no regulator, review or study among them):

1 community or commercial page, not counted here.

Eaten or drunk Swap

Under the default Cautious lens red 27 lake (ci 45410) in food and drink rates Swap: the app would put this near the top of your swap plan. Mainstream (consensus only) rates it Watch; Based (adds the fringe) rates it Swap. Researched 2026-09-03.

Sourced concerns (2)

ConsensusRestrictedconfidence 80%

Red 27 Lake (CI 45410) is approved for use as a color additive in specified amounts in foods, drugs, and cosmetics by the U.S. Food and Drug Administration (FDA).

Why here: This regulatory approval directly addresses the safety for ingestion as it permits use in food and pharmaceuticals.
What would have to be true: Ingested as a color additive in foods and pharmaceuticals, conforming to FDA specifications and batch certification requirements.
The other side: None, this is a regulatory approval based on safety assessments.

Sources the engine cites:

Red 27 Lake - Cosmetics Info — cosmeticsinfo.org (2026) · regulator or public body
1 web article (oasishealth.app), linked in the app.

EmergingEnvironmentalconfidence 70%

As an organohalogen compound, CI 45410 (Red 27 Lake) is associated with the general concerns of persistence in the environment and chronic health issues often found with this class of chemicals.

Why here: Ingestion of persistent substances can lead to chronic exposure and potential health effects.
What would have to be true: Ingestion of products containing the substance, leading to potential chronic exposure due to its persistence.
The other side: While organohalogens are often associated with bioaccumulation, modeled results for Solvent Red 48 (CI 45410) suggest it is not bioaccumulative, although it is expected to be persistent in water, soil, and sediment.

Sources the engine cites:

Screening Assessment for the Challenge — canada.ca (2024) · regulator or public body

Not researched here

The engine has no dossier for red 27 lake (ci 45410) when cooked with heat, in cold food, as a finishing ingredient, in heated food packaging or other uses. The app researches an ingredient for the use it infers from your product, so a scan fills these in; this page only shows what has already been researched and source-verified.

This is research, not medical advice. Detox My Life shows sourced claims sorted by evidence tier. It does not diagnose, treat, or tell you to start or stop anything. Talk to a qualified professional about your health.

Scan your own. The app reads any product label with your camera, works out how you are about to use it, and researches every ingredient for that use with live sources. Every scan adds to a Detox Score for your home, where 50 is a typical home in your region, and a plan of next swaps.

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