Is Acetyl Tributyl Citrate safe on skin (left on)?
Cosmetics1 use researched1 sourced claims
Where it turns up: plasticiser, nail polish flexibility, common. Detox My Life researched acetyl tributyl citrate under one use, because the same substance means something different in each use. Every claim below carries its evidence tier, how sure the research is that it applies here, and the sources it cites. The level is computed by the app's own deterministic engine, so the page says exactly what the app would.
Level by use and lens
| Use | Mainstream | Cautious (default) | Based | Concerns · favour · fringe |
| On skin, left on | Clean | Low | Low | 1 · 0 |
Mainstream shows consensus claims only; Cautious adds emerging research; Based adds fringe claims, labelled as such. The last column counts, under Cautious, the sourced concerns, the findings in its favour and the fringe claims Based would add.
Safer swaps: the app's swap catalog covers the products this turns up in: Nail polish. Alternatives are always types, never brands.
On skin, left on Low
Under the default Cautious lens acetyl tributyl citrate on skin (left on) rates Low: a little concern, nothing the app would ask you to swap. Mainstream (consensus only) rates it Clean; Based (adds the fringe) rates it Low. Researched 2026-09-03.
Sourced concerns (1)
EmergingEndocrineconfidence 70%
In in vitro structural binding studies, acetyl tributyl citrate has been found to bind to human sex hormone-binding globulin (SHBG), suggesting it may interfere with sex steroid homeostasis.
- Why here
- Acetyl tributyl citrate is used as a plasticizer and emollient in dermal leave-on cosmetic products, which could lead to dermal absorption and potential systemic exposure.
- What would have to be true
- Systemic exposure to acetyl tributyl citrate following dermal absorption from leave-on cosmetic products.
Sources the engine cites:
Not researched here
The engine has no dossier for acetyl tributyl citrate when cooked with heat, in cold food, as a finishing ingredient, in heated food packaging or other uses. The app researches an ingredient for the use it infers from your product, so a scan fills these in; this page only shows what has already been researched and source-verified.
This is research, not medical advice. Detox My Life shows sourced claims sorted by evidence tier. It does not diagnose, treat, or tell you to start or stop anything. Talk to a qualified professional about your health.
Scan your own. The app reads any product label with your camera, works out how you are about to use it, and researches every ingredient for that use with live sources. Every scan adds to a Detox Score for your home, where 50 is a typical home in your region, and a plan of next swaps.
See also: all ingredients · paste a label to check it · how to read an ingredient flag